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Failover should take no more than five minutes, and ideally less than two minutes The best way to achieve this goal is for the takeover server to already be booted up and running as many of the underlying system processes as possible If a full reboot is required in order to failover, failover times will go way up and can, in some cases, take an hour or more The two- to five-minute goal for failovers is a noble one and can be easily met by most applications The most glaring exception to this is databases such as Oracle or DB2 Databases can only be restarted after all of the transactions that have been cached are rerun, and the database updated (Transactions are cached to speed up routine database performance; the trade-off is a slowing of recovery time.

) There is no limit to how long it might take a database to run through all of the outstanding transactions, and while those transactions are being rerun, the database is down from a user s perspective Minimal manual intervention Ideally, no human intervention at all should be required for a failover to complete; the entire process should be automated Some sites or applications may require manual initiation for a failover, but that is not generally desirable As already discussed, the host receiving a failover should never require a reboot Guaranteed data access After a failover, the receiving host should see exactly the same data as the original host Replicating data to another host when disks are not shared adds unnecessary risk and complexity, and is not advised for hosts that are located near to each other.

Sensors that employ antibodies or chemoreceptors for chemical recognition often show fast responses, but take inordinate amounts of time to regenerate baseline readings in recovery time studies This nding is primarily a result of the large association constants of these species for their speci c binding partners, with association kinetics being rapid, and dissociation kinetics being very slow Chaotropic reagents and denaturants are often used ex situ, to decrease the af nity of the recognition agent for its ligand by interfering with hydrogen bonding or by reversibly altering the tertiary structure of the protein Biosensors are also evaluated with respect to their stability The reproducible generation of signal for a given analyte concentration is evaluated with respect to storage time, under various conditions of temperature and pH, and the results indicate the storage stability of the sensor.

The systems in a failover configuration should also communicate with each other continuously, so that each system knows the state of its partner This communication is called a heartbeat Later in this chapter we discuss the implications when the servers lose their heartbeats..

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